Class
|
Drug
|
Neuroleptic Malignant Syndrome
|
Parkinsonism
|
Acute or Tardive Dyskinesia
|
Akathesia
|
Tardive Dyskinesia
|
Tremor
|
Chorea
|
Myoclonus
|
Tic
|
Antidepressants
|
Tricyclics
|
|
x
|
x
|
xx
|
xx
|
50%
|
Rare
|
9-40%
|
|
Monamine Oxidase Inhibitors
|
|
x
|
x
|
x
|
|
15%
|
|
xx
|
|
SSRIs
|
|
x
|
xx
|
xx
|
x
|
8%
|
x
|
xx
|
x
|
Trazodone
|
|
x
|
|
|
|
|
x
|
x
|
|
Buproprion
|
|
x
|
x
|
x
|
x
|
|
x
|
|
|
Effexor
|
|
4%
|
2%
|
x
|
|
5%
|
|
3%
|
|
Celexa
|
|
x
|
x
|
|
x
|
|
|
x
|
|
Serzone
|
x
|
x
|
x
|
x
|
|
xx
|
|
xx
|
|
Remeron
|
|
x
|
x
|
x
|
x
|
7%
|
x
|
x
|
|
Anxiolytics
|
Buspirone
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Diazepam
|
|
x
|
x
|
x
|
x
|
Withdrawal
|
|
x
|
|
Clonazepam
|
|
x
|
x
|
x
|
x
|
Withdrawal
|
|
x
|
|
Lithium
|
|
x
|
|
x
|
x
|
50 - 65%
|
x
|
x
|
|
Stimulants
|
Amphetamines
|
|
x
|
x
|
x
|
x
|
xx
|
x
|
x
|
xxx
|
Cocaine
|
|
x
|
x
|
x
|
x
|
xx
|
x
|
x
|
xxx
|
Methylphenidate
|
|
x
|
x
|
x
|
x
|
xx
|
x
|
x
|
xxx
|
Anticonvulsants
|
Valproic Acid
|
|
xx
|
xx
|
x
|
x
|
xx
|
x
|
xxx
|
|
Carbamazepine
|
x
|
|
x
|
|
x
|
x
|
|
|
x
|
Topiramate
|
|
|
|
|
|
6%
|
x
|
|
|
Diphenylhydantoin
|
|
x
|
xx
|
|
x
|
xx
|
xxxx
|
xxx
|
|
Phenobarb
|
|
|
x
|
|
x
|
|
x
|
x
|
|
Gabapentin
|
|
|
x
|
|
|
xxx
|
x
|
xxx
|
|
Lamotrigine
|
|
|
x
|
|
|
x
|
x
|
|
|
Antipsychoics (Typical)
|
|
xxxx
|
xxxx
|
xxxx
|
xxx
|
xxx
|
xxx
|
xxx
|
xxx
|
xxx
|
Antipsychotics (Atypical)
|
Risperidone
|
|
7-13%
|
3%
|
3%
|
x
|
2%
|
|
|
|
Olanzepine
|
|
12-15%
|
2-3%
|
5%
|
5-10%
|
4%
|
|
2%
|
|
Seroquel
|
|
4-6%
|
|
2%
|
|
x
|
|
|
|
Clozapine
|
|
3%
|
|
3%
|
1%
|
6%
|
|
|
|
Class
|
Drug
|
Neuroleptic Malignant Syndrome
|
Parkinsonism
|
Acute or Tardive Dyskinesia
|
Akathesia
|
Tardive Dyskinesia
|
Tremor
|
Chorea
|
Myoclonus
|
Tic
|
H1 Antihistamines
|
Chlorphenipramine
|
|
x
|
|
x
|
x
|
x
|
|
|
|
H2 Antihistamines
|
Cimetidine
|
|
xx
|
x
|
x
|
|
xx
|
x
|
|
|
Ranitidine
|
|
xx
|
x
|
x
|
|
xx
|
x
|
|
|
Anticholinergics
|
Trihexiphenidyl
|
|
|
|
|
x
|
|
x
|
|
|
Cogentin
|
|
|
|
|
x
|
|
x
|
|
|
Cholinergics
|
Bethanocol
|
|
x
|
|
|
|
|
|
x
|
|
Pyridostigmine
|
|
x
|
|
|
|
|
|
x
|
|
Antibiotics
|
Amphoteracin B
|
|
x
|
|
|
|
|
|
|
|
Penicillin
|
|
|
|
|
|
|
|
xx
|
|
Cephalosporins
|
|
|
|
|
|
|
|
xx
|
|
Septra
|
|
x
|
|
|
|
x
|
|
|
|
Chloroquine
|
|
|
x
|
|
|
|
|
|
|
Adenosine Arabinoside
|
|
|
|
|
|
x
|
|
|
|
Acyclovir
|
|
|
|
|
|
|
x
|
|
|
Izoniazid
|
|
|
|
|
|
|
|
x
|
|
Cardiac Drugs
|
Amiodarone
|
|
x
|
|
|
x
|
xx
|
|
x
|
|
|
Digoxin
|
|
|
|
|
|
|
xx
|
|
|
Anti Neoplastics
|
Cytosine Arabinoside
|
|
x
|
|
|
|
|
|
|
|
Vincristine
|
|
x
|
|
|
|
|
x
|
|
|
Methotrexate
|
|
x
|
|
|
|
|
|
|
|
5-Fluoruracil
|
|
x
|
x
|
|
|
|
|
|
|
Doxyrubicin
|
|
x
|
x
|
|
|
|
|
|
|
Class
|
Drug
|
Neuroleptic Malignant Syndrome
|
Parkinsonism
|
Acute or Tardive Dyskinesia
|
Akathesia
|
Tardive Dyskinesia
|
Tremor
|
Chorea
|
Myoclonus
|
Tic
|
Oral Contraceptives
|
|
|
x
|
|
|
|
|
xxx
|
|
|
Opiates
|
Meperidine
|
|
x
|
|
x
|
|
|
|
x
|
x
|
Morphine
|
|
x
|
|
|
|
|
|
xx
|
xxx
|
Oxycodone
|
|
x
|
|
|
|
|
|
x
|
x
|
Methadone
|
|
|
|
|
|
|
x
|
x
|
|
Fentenyl
|
|
|
x
|
|
x
|
x
|
x
|
|
|
Calcium Channel Blockers
|
Verapamil
|
|
xx
|
|
|
|
|
|
|
|
Diltiazem
|
|
xx
|
|
|
|
xx
|
|
|
|
Flunarazine
|
|
xx
|
|
|
|
xx
|
|
|
|
AntiNauseants
|
Metochlopramide
|
x
|
xxx
|
xx
|
xx
|
xxx
|
xxx
|
xx
|
xx
|
|
Stemetil
|
x
|
xxx
|
xx
|
xx
|
xxx
|
xxx
|
xx
|
xx
|
|
Others
|
Naproxen sodium
|
|
x
|
|
|
|
|
|
|
|
Ethanol (Toxic or withdrawal)
|
|
x
|
|
|
|
xx
|
|
|
|
Procaine
|
|
x
|
|
|
|
|
|
|
|
Etretinate
|
|
x
|
|
|
|
|
|
|
|
Sumatryptan
|
|
|
x
|
|
|
|
|
|
|
Methylsergide
|
|
|
|
x
|
|
|
|
|
|
Cyproheptadine
|
|
|
|
x
|
|
|
x
|
x
|
|
Theophyline
|
|
|
|
|
|
xxx
|
|
|
|
Thyroxine
|
|
|
|
|
|
xxx
|
|
|
|
Hypoglycemics
|
|
|
|
|
|
xxx
|
|
|
|
Steroids
|
|
|
|
|
|
xxx
|
x
|
|
|
Nicotinic Acid
|
|
|
|
|
|
xxx
|
|
|
|
Baclofen
|
|
|
|
|
|
|
x
|
|
|
Tryptophan
|
|
|
|
|
|
|
|
x
|
|
Propofol
|
|
|
|
|
|
|
|
x
|
|